(RJ Jhonson) Rosemary (Rosmarinus officinalis) essential oil (ROEO) has been identified as a potential alternative treatment for stress. A study published in BMC Complementary and Alternative Medicinelooked into ROEO’s potential as a treatment for mood disorders resulting from chronic stress.
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by RJ Jhonson, June 21st, 2018
- The researchers had six-week-old ICR mice inhale ROEO and subjected them to tail suspension test (TST).
- They also examined ROEO-treated PC12 cells to determine the neuronal differentiation effect of ROEO in vitro.
- The authors measured intracellular acetylcholine, choline, and Gap43 gene expression levels.
- They noted a decrease in the mice’s immobility time during the TST, accompanied by an increase in dopamine levels in the animals’ brain.
- The researchers found that the modulation of intracellular acetylcholine, choline, and Gap43 gene expression levels resulted in a PC12 differentiation-induction effect.
- They believed ROEO activated the stress response system and caused the production of dopamine.
- The effect was attributed to α-pinene, an anxiolytic compound found in rosemary.
The researchers concluded that their findings were sufficient proof of ROEO’s anti-stress properties, making it potentially effective against mood disorders. They added that a clinical trial would be needed to determine ROEO’s effect on clinical depression.
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Read the full text of this study at this link.
Journal Reference:
Villareal MO, Ikeya A, Sasaki K, Arfa AB, Neffati M, Isoda H. ANTI-STRESS AND NEURONAL CELL DIFFERENTIATION INDUCTION EFFECTS OF ROSMARINUS OFFICINALIS L. ESSENTIAL OIL. BMC Complementary and Alternative Medicine. 11 September 2017;17(1). (549). DOI: 10.1186/s12906-017-2060-1
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