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Mouse Study Finds Bpa Exposure Has Transgenerational Effects on Gene Linked to Autism

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(Neuroscience News) Transgenerational bisphenol A (BPA) exposure may contribute to autism, according to a mouse study published in the Endocrine Society’s journal Endocrinology.

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Source – Neuroscience News

by Staff Writer, June 15th, 2019

Endocrine disrupting chemicals (EDCs) are chemicals or mixtures of chemicals that interfere with the way the body’s hormones work. BPA is a common EDC used in plastics and food storage material, and it is already present in most humans’ urine or blood. Animal studies have linked BPA to anxiety, aggression, and poor learning and social interactions. Studies of human populations report associations between BPA and neurobehavioral issues like attention deficit hyperactivity disorder and autism.

“Exposure of mouse fetuses to BPA disrupts formation of nerve cell connections in the brain, and this is a transgenerational effect,” said the study’s senior author, Emilie F. Rissman, Ph.D., of University of Virginia School of Medicine in Charlottesville, Va. and North Carolina State University in Raleigh, N.C. “To put this in human terms, if your great grandmother was exposed to BPA during her pregnancy and none of your other relatives ever came into contact with BPA, your brain would still show these effects.”

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In this mouse study, researchers tested mice descended from those exposed to BPA for social recognition and found that they showed a social behavioral deficient like autistic behavior. The image is credited to NIH/NIEHS.

In this mouse study, researchers tested mice descended from those exposed to BPA for social recognition and found that they showed a social behavioral deficient like autistic behavior. Mice whose great grandmothers were exposed to BPA during pregnancy were more active and took longer to habituate to strangers than other mice. More strikingly, they didn’t explore the new mice that were introduced to the group. Mice are very social and curious, so this is an exciting finding.

“Even if we ban all BPA right now, that will not change these long-term effects on the brain,” Rissman said.

Other authors of the study include: Jennifer T. Wolstenholme of the University of Virginia School of Medicine in Charlottesville, Va., and Virginia Commonwealth University in Richmond, Va.; Zuzana Drobná and Joshua W. Irvin of North Carolina State University; Anne D. Henriksen of James Madison University in Harrisonburg, Va.; Jessica A. Goldsby of the University of Virginia School of Medicine; Rachel Stevenson of Virginia Commonwealth University; and Jodi A. Flaws of the University of Illinois in Urbana, Ill.

Funding: The study received funding support from the National Institutes of Health and the Environmental Protection Agency.

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Stillness in the Storm Editor: Why did we post this?

The preceding information reveals the corruption, malpractice and incompetence of mainstream medical institutions and related organizations. This information is important to comprehend so as to dispel any false trust you have with these institutions—which could cost you or your loved ones their life. That said, one should be intelligent with their health choices. We are not advocating for completely abandoning all modern medical services. We are simply encouraging you not to trust the system blindly. Be sure to ask plenty of questions, get second opinions, and do your own research as much as possible. We do not live in a world where one can blindly trust any government-dependent institution. With this hard truth firmly understood, one can begin the slow process of developing their own expertise insofar as health.

– Justin

Not sure how to make sense of this? Want to learn how to discern like a pro? Read this essential guide to discernment, analysis of claims, and understanding the truth in a world of deception: 4 Key Steps of Discernment – Advanced Truth-Seeking Tools.

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Source:

https://neurosciencenews.com/bpa-asd-transgenerational-14241/

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